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著作

著作

  1. Chan TYK. Worldwide occurrence and investigations of contamination of herbal medicines by tropane alkaloids. Toxins 2017; 9: 284: 1-10.
  2. Chan TYK. Regional variations in the risk and severity of ciguatera caused by eating moray eels. Toxins 2017; 9: 201:1-11.
  3. Hon KL, Chan MH, Ng MH, Ho CC, Tsang KY, Tam WH, Ho CS. Urine Comprehensive Drug Screen, Low Birth Weight and Withdrawal Symptoms in a Neonatal Unit: A Case Control Study. Curr Clin Pharmacol 2016; 11(4):274-281
  4. Chan TYK. Emergence and epidemiology of Haff disease in China. Toxins 2016; 8: 359:1-9.
  5. Hu M, Lee HK, To KKW, Fok BSP, Wo SK, Ho CS, Wong CK, Zuo Z, Chan TYK, Chan JCN, Tomlinson B. Telmisartan increases systemic exposure to rosuvastatin after single and multiple doses, and in vitro studies show telmisartan inhibits ABCG2-mediated transport of rosuvastatin. European Journal of Clinical Pharmacology 2016; 72: 1471-1478.
  6. Chan TYK. Fatal anaphylactic reactions to lignocaine. Forensic Science International 2016; 266: 449-452.
  7. Chan TYK. Herbal medicines induced anticholinergic poisoning in Hong Kong. Toxins 2016; 8: 80:1-6.
  8. Chan TYK. Characteristic features and contributory factors in fatal ciguatera fish poisoning – Implications for prevention and public education. American Journal of Tropical Medicine and Hygiene 2016; 94: 704-709.
  9. Chan TYK. Aconitum alkaloid poisoning because of contamination of herbs by aconite roots. Phytotherapy Research 2016; 30: 3-8.
  10. Chan TYK. Ciguatoxic potential of brown-marbled grouper in relation to fish size and geographical origin. American Journal of Tropical Medicine and Hygiene 2015; 93: 1117-1121.
  11. Chan TYK. Ciguatera fish poisoning in East Asia and Southeast Asia. Marine Drugs 2015; 13: 3466-3478.
  12. Chan TYK. Incidence and causes of Aconitum alkaloid poisoning in Hong Kong from 1989 to 2010. Phytotherapy Research 2015; 29: 1107-1111.
  13. Chan TYK. Emergence and epidemiology of ciguatera in the coastal cities of Southern China. Marine Drugs 2015; 13: 1175-1184.
  14. Chan TYK. Epidemiology and clinical features of ciguatera fish poisoning in Hong Kong. Toxins 2014; 6: 2989-2997.
  15. Chan TYK. Pharmacovigilance in Hong Kong. In: Andrews EB, Moore N, editors. Mann's Pharmacovigilance. 3rd Edition, West Sussex: John Wiley & Sons, 2014: 259-261.
  16. Chan TYK. Aconitum alkaloid poisoning related to the culinary uses of aconite roots. Toxins 2014: 6: 2605-2611.
  17. Chan TYK. Large outbreaks of ciguatera after consumption of brown marbled grouper. Toxins 2014: 6: 2041-2049.
  18. Chan TYK, Joynt GM. Prolonged profound hypotension complicating severe methyldopa overdose. International Journal of Clinical Pharmacology and Therapeutics 2014; 52: 628-630.
  19. Chang Q, Wo SK, Ngai KLK, Wang X, Fok B, Ngan TM, Wong VT, Chan TYK, Lee VHL, Tomlinson B, Chan PKS, Chow MSS, Zuo Z. Bench to bed evidences for pharmacokinetic and pharmacodynamic interactions involving oseltamivir and Chinese medicine. Evidence-Based Complementary and Alternative Medicine 2014; 2014, 354172. http://dx.doi.org/10.1155/2014/354172
  20. Chan TYK. Zopiclone induced methemoglobinemia and hemolytic anemia. International Journal of Clinical Pharmacology and Therapeutics 2014; 52: 402-406.
  21. Chan TYK. Ciguatera caused by consumption of humphead wrasse. Toxicon 2013; 76: 255-259.
  22. Tang HL, Mak YF, Chu KH, Lee W, Fung SKS, Chan TYK, Tong KL. Minimal change disease caused by exposure to mercury-containing skin lightening cream: a report of 4 cases. Clinical Nephrology 2013; 79: 326-329.
  23. Chan TYK. Severe bradycardia and prolonged hypotension in ciguatera fish poisoning. Singapore Medical Journal 2013; 54: e120-e122.
  24. Chan TYK. Contributory factors in herb-induced fatal aconite poisoning. Forensic Science International 2012; 223: 40-43.
  25. Chan TYK. Aconite poisoning following the percutaneous absorption of Aconitum alkaloids. Forensic Science International 2012; 223: 25-27.
  26. Wong SK, Sin DWM, Kaarls R, Sargent M, Chu XG, Chan TYK, Lam CW, Seta K. International symposium on "Food and Health: from Measurement Science to Quality and Safety". Accreditation and Quality Assurance 2012; 17: 557-560
  27. Hon EKL, Leung TF, Yau HC, Chan TYK. Paradoxical use of oral and topical steroids in steroidphobic patients resorting to traditional Chinese medicines. World Journal Pediatrics 2012; 8: 263-267.
  28. Chan TYK. Aconitum alkaloid content and the high toxicity of aconite tincture. Forensic Science International 2012; 222: 1-3.
  29. Zhang W, Chan TYK, Fan L, Guo Y, Zhou HH. Translating pharmacogenomics into personalized medicine and drug development. Personalized Medicine 2012; 9: 93-97.
  30. Chen SPL, Ng SW, Poon WT, Lai CK, Ngan T, Tse ML, Chan TYK, Chan AWY, Mak TWL. Aconite poisoning over 5 years: a case series in Hong Kong and lessons towards herbal safety. Drug Safety 2012; 35: 575-587.
  31. Chan TYK. Vegetable-borne nitrate and nitrite and the risk of methaemoglobinaemia. Toxicology Letters 2011; 200: 107-108.
  32. Chan TYK. Causes and prevention of herb-induced aconite poisonings in Asia. Human and Experimental Toxicology. 2011; 30: 2023-2026.
  33. Chan TYK, Chiu SW. Wild mushroom poisonings in Hong Kong. Southeast Asian Journal of Tropical Medicine and Public Health. 2011; 42: 468-469.
  34. Chan TYK. Inorganic mercury poisoning associated with skin-lightening cosmetic products. Clinical Toxicology 2011; 49: 886-891.
  35. Chan TYK, Hung LK. Digital gangrene following a green pit viper bite. Southeast Asian Journal of Tropical Medicine and Public Health 2010; 41: 192-194.
  36. Chan TYK. Hidden aconite roots in herbal medicines. Clinical Toxicology 2010; 48: 92.
  37. Chan TYK. Outbreaks of severe hypoglycaemia due to illegal sexual enhancement products containing undeclared glibenclamide. Pharmacoepidemiology and Drug Safety 2009; 18: 1250-1251.
  38. Chan TYK. Aconite poisoning presenting as hypotension and bradycardia Human and Experimental Toxicology 2009; 28: 795-797.
  39. Chan TYK. Overdose of methyldopa, indapamide and theophylline resulting in prolonged hypotension, marked diuresis and hypokalaemia in an elderly patient. Pharmacoepidemilogy and Drug Safety 2009; 18: 977-979.
  40. Chan TYK. Life-threatening retroperitoneal bleeding due to warfarin-drug interactions. Pharmacoepidemiology and Drug Safety 2009; 18:420-422.
  41. Chan TYK. Aconite poisoning. Clinical Toxicology 2009; 47:279-285.
  42. Chan TYK. Potential risks associated with the use of herbal anti-obesity products. Drug Safety 2009; 32:453-6.
  43. Leung H. Hung A. Hui AC. Chan TYK. Warfarin overdose due to the possible effects of Lycium barbarum L. Food and Chemical Toxicology 2008; 46: 1860-1862.
  44. Chan TYK. Preventing medication error and unintentional drug poisoning in the elderly (Editorial). Hong Kong Medical Journal 2006; 12: 332-333.
  45. Chan TYK. A probably case of amygdalin-induced peripheral neuropathy in a vegetarian with vitamin B12 deficiency. Therapeutic Drug Monitoring 2006; 28: 140-141.
  46. Kwok JSS, Chan TYK. Recurrent heat-related illnesses during antipsychotic treatment. Annals of Pharmacotherapy 2005; 39: 1940-1942.
  47. Chan TYK, Tam HP, Lai CK, Chan AYW. A multidisciplinary approach to the toxicological problems associated with the use of herbal medicines. Therapeutic Drug Monitoring 2005; 27: 53-57.
  48. Lin CC, Chan TYK, Deng JF. Clinical features and management of herb-induced aconitine poisoning. Annals of Emergency Medicine 2004; 43: 574-579.
  49. Wong ALN, Chan TYK. Interaction between warfarin and the herbal product guilinggao. Annals of Pharmacotherapy 2003; 37: 836-838.
  50. Wong ALN, Chan JTS, Chan TYK. Adverse herbal interactions causing hypotension. Therapeutic Drug Monitoring 2003; 25: 297-298.
  51. Soo YOY, Wong CH, Griffith JF, Chan TYK. Subcutaneous injection of metallic mercury. Human and Experimental Toxicology 2003; 22: 345-348.
  52. Wong RSM, Cheng G, Chan TYK. Use of herbal medicines by patients receiving warfarin. Drug Safety 2003; 26: 585-588.
  53. Chan TYK. Herbal medicine causing possible strychnine poisoning. Human and Experimental Toxicology 2002; 21: 467-468.
  54. Chan TYK. Incidence of herb-induced aconitine poisoning in Hong Kong: impact of publicity measures to promote awareness among the herbalists and the public. Drug Safety 2002; 25: 823-828.
  55. Chan TYK. Ingestion of medicated oils by adults: the risk of severe salicylate poisoning is related to the packaging of these products. Human and Experimental Toxicology 2002; 21: 171-174.
  56. Chan TYK, Kwok TCY. Chronicity of neurological features in ciguatera fish poisoning. Human and Experimental Toxicology 2001; 20: 426-428.
  57. Chan TYK. Food-borne clenbuterol may have potential for cardiovascular effects with chronic exposure (commentary). Journal of Toxicology Clinical Toxicology 2001; 39: 345-348.
  58. Chan TYK. Vegetable-borne methamidophos poisoning. Journal of Toxicology Clinical Toxicology 2001; 39: 337-338.
  59. Chan TYK. Fulminant hepatic failure due to acetaminophen poisoning may be less common in Hong Kong. Journal of Toxicology Clinical Toxicology, 2001; 39: 175-177.
  60. Chan TYK. Poisonings in Hong Kong. Doctor of Philosophy in Medical Sciences Thesis, The Chinese University of Hong Kong, June 2000, 363 pages.
  61. Chan TYK. Improvements in the packaging of drugs and chemicals can reduce the likelihood of severe intentional poisonings in adults. Human and Experimental Toxicology 2000; 19: 387-391.
  62. Critchley JAJH, Zhang Y, Suthisisang CC, Chan TYK, Tomlinson B. Alternative therapies and medical science: designing clinical trials of alternative/complementary medicine – is evidence-based traditional Chinese medicine attainable? Journal of Clinical Pharmacology 2000, 40: 462-467.
  63. Tomlinson B, Chan TYK, Chan JCN, Critchley JAJH, But PPH. Toxicity of complementary therapies: an Eastern perspective. Journal of Clinical Pharmacology 2000; 40: 451-456.
  64. Chan TYK. Health hazards due to clenbuterol residues in food. Journal of Toxicology Clinical Toxicology 1999; 37: 517-519.
  65. Leung VKS, Chan TYK, Yeung VTF. Amitraz poisoning in humans. Journal of Toxicology Clinical Toxicology 1999; 37: 513-514.
  66. Chan TYK. Childhood poisoning: the scope for prevention. Veterinary and Human Toxicology 1998; 40: 361-363.
  67. Chan TYK. Lengthy persistence of ciguatoxin in the body. Transactions of the Royal Society of Tropical Medicine and Hygiene 1998; 92: 662.
  68. Chan TYK. An assessment of the delayed effects associated with valerian overdose. International Journal of Clinical Pharmacology and Therapeutics 1998; 36: 569.
  69. Chan TYK. Trends in hospitalizations and mortality due to medicinal or non-medicinal poisonings in Hong Kong. Veterinary and Human Toxicology 1997; 39: 372-373.
  70. Luk JKH, Yeung VTF, Chan TYK. Elevated blood mercury following the ingestion of mercurochrome. Journal of Toxicology Clinical Toxicology 1997; 35: 657-658.
  71. Chan TYK. Packaging of drugs and the risk of severe toxicity in adult self-poisonings (Editorial). Journal of Clinical Pharmacy and Therapeutics 1997; 22: 157-158.
  72. Chan TYK. Food delicacies as a cause of natural toxin poisonings in Hong Kong (Invited article). Toxicology and Ecotoxicology News/Reviews 1997; 4: 124-126.
  73. Chan TYK. Monitoring the safety of herbal medicines (Leading article). Drug Safety 1997; 17: 209-215.
  74. Critchley JAJH, Critchley LA, Yeung EA, Young RP, Young RJ, Chan TYK, Goh VK. Granulocyte-colony stimulating factor in the treatment of colchicine poisoning. Human and Experimental Toxicology 1997; 16: 229-232.
  75. Chan TYK, Chan AYW, Pang CW. Epidemiology of poisoning in the New Territories South of Hong Kong. Human and Experimental Toxicology 1997; 16: 204-207.
  76. Chan TYK. Safety packaging of acetaminophen combination preparations and severity of adult poisoning. Journal of Toxicology Clinical Toxicology 1996; 34: 747-749.
  77. Chan TYK, Tam LS, Chan LY. Stonefish sting: an occupational hazard in Hong Kong. Annals of Tropical Medicine and Parasitology 1996; 90: 675-676.
  78. Chan TYK. The epidemiology of acetaminophen (paracetamol) poisoning in Hong Kong. Veterinary and Human Toxicology 1996; 38: 443-444.
  79. Chan TYK, Critchley JAJH, Chan AYW. An estimate of the incidence of pesticide poisoning in Hong Kong. Veterinary and Human Toxicology 1996; 38: 362-364.
  80. Chan TYK, Critchley JAJH. Pulmonary aspiration following Dettol poisoning: the scope for prevention. Human and Experimental Toxicology 1996; 15: 843-846.
  81. Chan TYK, Chan AYW, Critchley JAJH. Factors responsible for continuing morbidity after paracetamol poisoning in Chinese patients in Hong Kong. Singapore Medical Journal 1996; 37: 275-277.
  82. Chan TYK. Potential dangers from topical preparations containing methyl salicylate. Human and Experimental Toxicology 1996; 15: 747-750.
  83. Chan TYK, Chan AWK. Aminopyrine-induced blood dyscrasias: still a problem in many parts of the world. Pharmacoepidemiology and Drug Safety 1996; 5: 215-219.
  84. Chan TYK. Salicylamide toxicity in overdose. International Journal of Clinical Pharmacology and Therapeutics 1996; 34: 366.
  85. Chan TYK, Critchley JAJH. Childhood poisoning in Hong Kong. Hong Kong Medical Journal 1996; 2: 191-195.
  86. Chan TYK. Food-borne nitrates and nitrites as a cause of methemoglobinemia. Southeast Asian Journal of Tropical Medicine and Public Health 1996; 27: 189-192.
  87. Chan TYK. Propoxyphene overdose in Chinese subjects. Journal of Toxicology Clinical Toxicology 1996; 34: 251-252.
  88. Chan TYK. Medicated oils and severe salicylate poisoning: quantifying the risk based on methyl salicylate content and bottle size. Veterinary and Human Toxicology 1996; 38: 133-134.
  89. Chan TYK. The risk of severe salicylate poisoning following the ingestion of topical medicaments or aspirin. Postgraduate Medical Journal 1996; 72: 109-112.
  90. Chan TYK, Critchley JAJH. Usage and adverse effects of Chinese herbal medicines. Human and Experimental Toxicology 1996; 15: 5-12.
  91. Lee KCC, Chan TYK, Chan AWK, Lau GSN, Critchley JAJH. Use and abuse of benzodiazepines in Hong Kong 1990-1993 - the impact of regulatory changes. Journal of Toxicology Clinical Toxicology 1995; 33: 597-602.
  92. Lau MSW, Chan TYK, Tomlinson B, Chan JCN, Anderson PJ, Lau GSN, Critchley JAJH. Role of the Drug and Poisons Information Bureau in monitoring the safety of Chinese herbal medicines in Hong Kong. Journal of Natural Toxins 1995; 4: 203-206.
  93. Chan TYK, Leung KP, Critchley JAJH. Poisoning due to common household products. Singapore Medical Journal 1995; 36: 285-287.
  94. Chan TYK, Critchley JAJH. Drug-related problems as a cause of hospital admissions in Hong Kong. Pharmacoepidemiology and Drug Safety 1995; 4: 165-170.
  95. Chan TYK, Tang CH, Critchley JAJH. Poisoning due to an over-the-counter hypnotic, Sleep-Qik (hyoscine, cyproheptadine, valerian). Postgraduate Medical Journal 1995; 71: 227-228.
  96. Chan TYK. Anticholinergic poisoning due to Chinese herbal medicines. Veterinary and Human Toxicology 1995; 37: 156-157.
  97. Chan TYK, Critchley JAJH, Chan AYW. Renal failure is uncommon in Chinese patients with paracetamol (acetaminophen) poisoning. Veterinary and Human Toxicology 1995; 37: 154-156.
  98. Chan TYK, Lee KKC, Chan AYW, Critchley JAJH. Poisoning due to Chinese proprietary medicines. Human and Experimental Toxicology 1995; 14: 434-436.
  99. Chan TYK, Critchley JAJH, Lau JTF. The risk of aspiration in Dettol poisoning: a retrospective cohort study. Human and Experimental Toxicology 1995; 14: 190-191.
  100. Chan TYK, Chan AYW, Ho CS, Critchley JAJH. The clinical value of screening for paracetamol in patients with acute poisoning. Human and Experimental Toxicology 1995; 14: 187-189.
  101. Chan TYK, Sung JJY, Critchley JAJH. Chemical gastro-oesophagitis, upper gastrointestinal haemorrhage and gastroscopic findings following Dettol poisoning. Human and Experimental Toxicology 1995; 14: 18-19.
  102. Chan TYK, Chan AYW, Ho CS, Critchley JAJH. The clinical value of screening for salicylates in acute poisoning. Veterinary and Human Toxicology 1995; 37: 37-38.
  103. Chan TYK, Tomlinson B, Tse LKK, Chan JCN, Chan WWM, Critchley JAJH. Aconitine poisoning due to Chinese herbal medicines - a review. Veterinary and Human Toxicology 1994; 36: 452-455.
  104. Chan TYK, Critchley JAJH, Chan JCN, Tomlinson B, Lau MSW, Anderson PJ, Lau GSN, So KWH. Childhood poisoning in Hong Kong: experience of the Drug and Poisons Information Bureau from 1988 to 1992. Journal of Paediatrics and Child Health 1994; 30: 453-454.
  105. Chan TYK, Critchley JAJH. Reporting of adverse drug reactions in relation to general medical admissions to a teaching hospital in Hong Kong. Pharmacoepidemiology and Drug Safety 1994; 3: 85-89.
  106. Chan TYK. Aconitine poisoning: a global perspective. Veterinary and Human Toxicology 1994; 36: 326-328.
  107. Chan TYK, Critchley JAJH. Adverse reactions to intravenous N-acetylcysteine in Chinese patients with paracetamol (acetaminophen) poisoning. Human and Experimental Toxicology 1994; 13: 542-544.
  108. Chan TYK, Critchley JAJH. An epidemiological study of snake bites in the New Territories East, Hong Kong. Annals of Tropical Medicine and Parasitology 1994; 88: 219-221.
  109. Chan TYK, Critchley JAJH, Chan MTV, Yu CM. Drug overdosage and other poisoning in Hong Kong - the Prince of Wales Hospital (Shatin) experience. Human and Experimental Toxicology 1994; 13: 512-515.
  110. Chan TYK, Critchley JAJH. The spectrum of poisonings in Hong Kong: an overview. Veterinary and Human Toxicology 1994; 36: 135-137.
  111. Chan TYK, Critchley JAJH, Chan JCN, Tomlinson B. Metabolic activation and paracetamol hepatotoxicity - an update on the management of paracetamol (acetaminophen) poisoning. Journal of the Hong Kong Medical Association 1994; 46: 87-92.
  112. Chan TYK, Chan JCN, Tomlinson B, Critchley JAJH. Clinical features and hospital management of bites by the white-lipped green pit viper (Trimeresurus albolabris). Southeast Asian Journal of Tropical Medicine and Public Health 1993; 24: 772-775.
  113. Chan TYK, Critchley JAJH. Hospitalizations due to acute pesticide poisoning in Hong Kong. Southeast Asian Journal of Tropical Medicine and Public Health 1993; 24: 769-771.
  114. Chan TYK, Chan JCN, Tomlinson B, Critchley JAJH. Chinese herbal medicines revisited - a Hong Kong perspective. Lancet 1993; 342: 1532-1534.
  115. Chan TYK, Lau MSW, Critchley JAJH. Serious complications associated with Dettol poisoning. Quarterly Journal of Medicine 1993; 86: 735-738.
  116. Chan TYK, Chan AYW, Critchley JAJH. Paracetamol poisoning and hepatotoxicity in Chinese - the Prince of Wales Hospital (Hong Kong) experience. Singapore Medical Journal 1993; 34: 299-302.
  117. Chan TYK, Critchley JAJH. The systems for monitoring adverse drug reactions in Hong Kong. Pharmacoepidemiology and Drug Safety 1993; 2: 145-148.
  118. Chan TYK, Critchley JAJH, Chan JCN, Tomlinson B, Lai VSM, Anderson PJ, Lau GSN. The Drug and Poisons Information Bureau at the Chinese University of Hong Kong. Journal of the Hong Kong Medical Association 1993; 45: 202-205.
  119. Chan TYK, Wang AYM. Life-threatening bradycardia and hypotension in a patient with ciguatera fish poisoning. Transactions of the Royal Society of Tropical Medicine and Hygiene 1993; 87: 71.
  120. Chan TYK, Tsoi WC, Critchley JAJH. The determinants of warfarin requirements in Chinese patients. Pharmacoepidemiology and Drug Safety 1992; 1: 281-282.
  121. Leung KP, Chan TYK, Sze FKH. Ciguatera poisoning in Hong Kong: a report of two cases. Southeast Asian Journal of Tropical Medicine and Public Health 1992; 23: 543-544.
  122. Chan TYK, Chan JCN, Tomlinson B, Critchley JAJH. Adverse reactions to drugs as a cause of admissions to a general teaching hospital in Hong Kong. Drug Safety 1992; 7: 235-240.


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